Parameters not working

Good Morning,

I'm using Report Builder 3.0 to create a report. Source is Oracle db and i have a sql that runs against the db to populate the report. Everything work fine . Now i want to add parameters (cascading). I have four parameters and all are set to select multiple values, Available Values- to get from query. Each of the parameters get their values from the four data sets that i created. When i add the parameters in the main query , like below

WHERE LOC IN (:LOC)

AND LASTNAME IN (:LASTNAME)

AND ID IN (:ID)

AND DESCR IN (:DESCR)

I run the report , select the parameter (the first one) , the whole report is blank, its not displaying any records. I tested using TOAD and works great there (the params)

Thanks